MRGPRG

Across TCGA pan-cancer cohorts, MRGPRG RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated MRGPRG data layer compared with 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher MRGPRG RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MRGPRG expression acts as an unfavorable survival marker, although some lineages such as OV and UCEC show a favorable association.

LUAD, LIHC, and COAD are the cancer types where MRGPRG RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	All	0.116	0.405	.002	63	view →
LIHC	OS	Tertile	All	0.051	0.783	<.001	54	view →
COAD	DFS	Tertile	III,IV	0.230	0.732	<.001	45	view →
UVM	OS	Tertile	All	0.218	0.696	.014	36	view →
OV	OS	Median	IV	0.915	0.615	<.001	36	view →
KIRC	DFS	Tertile	All	0.527	0.810	.002	24	view →
HNSC	OS	Tertile	All	0.288	0.608	.036	18	view →
THYM	DFS	Tertile	II,III,IV	0.145	0.873	<.001	18	view →
CESC	DFS	Tertile	IV	0.220	0.578	.010	18	view →
KIRP	OS	Tertile	II,III,IV	0.216	0.771	.049	9	view →
LUSC	DFS	Tertile	All	0.235	0.528	.047	6	view →
BLCA	DFS	Tertile	All	0.400	0.612	.044	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

MRGPRG–LUAD (OS)

Open the LUAD breakdown →