MRGPRG-AS1

Across TCGA cell cohorts, MRGPRG-AS1 protein abundance is significantly associated with the go_rna of many other GO terms, with 564 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MRGPRG-AS1-associated GO terms across cancer lineages are Lipoprotein particle mediated signaling, Actin filament-based transport, and Endothelial cell proliferation. Each is linked with MRGPRG-AS1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MRGPRG-AS1-to-partner and partner-to-MRGPRG-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lipoprotein particle mediated signaling grouped by MRGPRG-AS1-low versus MRGPRG-AS1-high in LUNG_SCLC.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRGPRG-AS1→partner) and Y-score (partner→MRGPRG-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Lipoprotein particle mediated signaling →	-0.366	-1.239	<.001	.001	3	3
BONE	Actin filament-based transport →	+0.198	+1.125	.002	<.001	3	3
BLOOD_Leukemia	Endothelial cell proliferation →	-0.084	-1.754	.009	.001	3	3
BLOOD_Leukemia	Pentose-phosphate shunt →	+0.116	+1.167	.007	.001	3	3
BONE	Mitotic cytokinetic process →	+0.152	+1.125	.001	<.001	3	3
BONE	DNA modification →	+0.081	+1.125	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 564 associations by consensus.

Lipoprotein particle mediated signaling by MRGPRG-AS1 expression — LUNG_SCLC

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