MRGPRG-AS1

Across TCGA pan-cancer cohorts, MRGPRG-AS1 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated MRGPRG-AS1 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher MRGPRG-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MRGPRG-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and UCEC show a favorable association.

READ, COAD, and BRCA are the cancer types where MRGPRG-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	DFS	Tertile	All	0.233	0.623	.002	54	view →
COAD	OS	Tertile	All	0.695	0.890	<.001	51	view →
BRCA	OS	Tertile	IV	0.408	0.805	.026	36	view →
LUAD	OS	Tertile	All	0.210	0.384	<.001	33	view →
UVM	DFS	Tertile	All	0.141	0.744	.024	18	view →
UCS	OS	Tertile	IV	1.000	0.307	.022	12	view →
LGG	DFS	Tertile	All	0.687	0.845	.004	9	view →
ESCA	DFS	Tertile	All	0.429	0.570	.023	8	view →
UCEC	DFS	Quartile	IV	1.000	0.590	.016	8	view →
CESC	OS	Tertile	All	0.764	0.533	.027	6	view →
LUSC	DFS	Quartile	III,IV	0.187	0.695	.025	4	view →
THCA	DFS	Quartile	III,IV	1.000	0.895	.039	1	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

MRGPRG-AS1–READ (DFS)

Open the READ breakdown →