MRGPRF

Across TCGA patient cohorts, MRGPRF protein abundance is significantly associated with the RNA expression of many other genes, with 8,784 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRGPRF-associated genes across cancer lineages are LDB2, PLN, and PLA2G5. Each is linked with MRGPRF in more than 5 cancer types. Because this analysis shows association rather than direction, both MRGPRF-to-partner and partner-to-MRGPRF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRGPRF versus LDB2 in UCEC, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRGPRF→partner) and Y-score (partner→MRGPRF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LDB2 →	+1.216	+1.007	<.001	<.001	3	6
PDAC	PLN →	+1.396	+0.989	<.001	<.001	3	6
PDAC	PLA2G5 →	+0.851	+0.997	<.001	<.001	3	5
UCEC	CNN1 →	+2.556	+1.060	<.001	<.001	3	5
UCEC	ABCA8 →	+1.594	+1.144	<.001	<.001	3	5
UCEC	CACNA1C →	+1.109	+1.014	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,784 associations by consensus.

MRGPRF vs LDB2 — UCEC

Explore this scatter interactively →