MRGPRF

Across TCGA cell cohorts, MRGPRF RNA expression is significantly associated with the go_rna of many other GO terms, with 1,448 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MRGPRF-associated GO terms across cancer lineages are Protein-containing complex disassembly, Positive regulation of cell-substrate adhesion, and Regulation of fibroblast proliferation. Each is linked with MRGPRF in more than 6 cancer types. Because this analysis shows association rather than direction, both MRGPRF-to-partner and partner-to-MRGPRF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein-containing complex disassembly grouped by MRGPRF-low versus MRGPRF-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRGPRF→partner) and Y-score (partner→MRGPRF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Protein-containing complex disassembly →	+0.036	+0.561	.001	.003	3	7
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cell-substrate adhesion →	+0.084	+0.810	<.001	.009	3	6
LARGE_INTESTINE	Regulation of fibroblast proliferation →	+0.058	+0.227	<.001	<.001	3	6
CNS	Positive regulation of fibroblast proliferation →	+0.113	+1.586	<.001	<.001	3	6
OVARY	Purine-containing compound biosynthetic process →	+0.032	+0.579	.009	.002	3	6
CNS	Regulation of smooth muscle cell migration →	+0.117	+1.442	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,448 associations by consensus.

Protein-containing complex disassembly by MRGPRF expression — OVARY

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