Across TCGA patient cohorts, MRGPRE RNA expression is significantly associated with the RNA expression of many other genes, with 13,138 significant associations in total. THYM shows the largest number of these associations.

The most reproducible MRGPRE-associated genes across cancer lineages are RUSC2, NOMO2, and FGFR1. Each is linked with MRGPRE in more than 19 cancer types. Because this analysis shows association rather than direction, both MRGPRE-to-partner and partner-to-MRGPRE results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRGPRE→partner) and Y-score (partner→MRGPRE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	RUSC2 →	+0.985	+0.144	<.001	<.001	3	20
THYM	NOMO2 →	+1.107	+0.174	<.001	<.001	3	20
STAD	FGFR1 →	+1.522	+0.413	<.001	<.001	3	20
THYM	GARRE1 →	+0.897	+0.121	<.001	.001	3	20
THYM	DENND5A →	+1.336	+0.240	<.001	<.001	3	20
THYM	GPRASP1 →	+1.290	+0.121	<.001	.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,138 associations by consensus.

Exploration

MRGPRE survival (RNA) · tumor vs normal (RNA) · all MRGPRE data types