MRGPRD

Across TCGA patient cohorts, MRGPRD mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible MRGPRD-associated genes across cancer lineages are GMP and DC. Each is linked with MRGPRD in more than 2 cancer types. Because this analysis shows association rather than direction, both MRGPRD-to-partner and partner-to-MRGPRD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP grouped by MRGPRD-low versus MRGPRD-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRGPRD→partner) and Y-score (partner→MRGPRD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	GMP →	+0.141	+2.416	<.001	.049	3	3
UCEC	DC →	+0.024	+3.234	.035	.009	3	2

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

GMP by MRGPRD expression — BLCA

Explore this box plot interactively →