MRFAP1

Across TCGA cell cohorts, MRFAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,496 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MRFAP1-associated GO terms across cancer lineages are Anaphase-promoting complex-dependent catabolic process, Regulation of aggrephagy, and Positive regulation of aggrephagy. Each is linked with MRFAP1 in more than 11 cancer types. Because this analysis shows association rather than direction, both MRFAP1-to-partner and partner-to-MRFAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Anaphase-promoting complex-dependent catabolic process grouped by MRFAP1-low versus MRFAP1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRFAP1→partner) and Y-score (partner→MRFAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Anaphase-promoting complex-dependent catabolic process →	+0.087	+0.829	.009	.007	3	12
BREAST	Regulation of aggrephagy →	+0.170	+0.723	<.001	.002	3	12
BREAST	Positive regulation of aggrephagy →	+0.197	+0.877	<.001	<.001	3	12
LARGE_INTESTINE	Establishment of spindle orientation →	+0.064	+0.551	<.001	<.001	3	11
LIVER	Positive regulation of chromosome condensation →	+0.142	+0.752	<.001	<.001	3	11
LIVER	Regulation of chromosome condensation →	+0.155	+0.888	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,496 associations by consensus.

Anaphase-promoting complex-dependent catabolic process by MRFAP1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →