MRE11

Across TCGA patient cohorts, MRE11 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,778 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRE11-associated proteins across cancer lineages are RAD50, ADNP, and U2AF2. Each is linked with MRE11 in more than 6 cancer types. Because this analysis shows association rather than direction, both MRE11-to-partner and partner-to-MRE11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRE11 versus RAD50 in COAD, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MRE11→partner) and Y-score (partner→MRE11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RAD50 →	+0.427	+0.353	.001	.003	3	7
LSCC	ADNP →	+0.408	+0.609	<.001	<.001	3	7
LSCC	U2AF2 →	+0.249	+0.583	<.001	<.001	3	6
UCEC	SSRP1 →	+0.367	+0.429	<.001	<.001	3	6
LSCC	MSH2 →	+0.677	+0.560	<.001	<.001	3	6
BRCA	NBN →	+0.242	+0.494	.001	<.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,778 associations by consensus.

MRE11 vs RAD50 — COAD

Explore this scatter interactively →