MRAS

Across TCGA patient cohorts, MRAS RNA expression is significantly associated with the RNA expression of many other genes, with 18,841 significant associations in total. UVM shows the largest number of these associations.

The most reproducible MRAS-associated genes across cancer lineages are SYNC, NACC2, and DIXDC1. Each is linked with MRAS in more than 29 cancer types. Because this analysis shows association rather than direction, both MRAS-to-partner and partner-to-MRAS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRAS versus SYNC in STAD, with a Pearson correlation of 0.77.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRAS→partner) and Y-score (partner→MRAS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	SYNC →	+1.630	+1.279	<.001	<.001	3	30
DLBC	NACC2 →	+1.265	+1.072	<.001	<.001	3	30
STAD	DIXDC1 →	+1.337	+1.205	<.001	<.001	3	30
KICH	FYCO1 →	+1.135	+1.276	.002	<.001	3	29
KICH	AZI2 →	+1.127	+1.255	<.001	<.001	3	29
CHOL	DENND5A →	+1.334	+1.367	<.001	<.001	3	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,841 associations by consensus.

MRAS vs SYNC — STAD

Explore this scatter interactively →