MRAP2

Across TCGA patient cohorts, MRAP2 mutation is significantly associated with the RNA expression of many other genes, with 813 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MRAP2-associated genes across cancer lineages are TDGF1P1, PAFAH1B2P1, and OR2J4P. Each is linked with MRAP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both MRAP2-to-partner and partner-to-MRAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TDGF1P1 grouped by MRAP2-low versus MRAP2-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRAP2→partner) and Y-score (partner→MRAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	TDGF1P1 →	+0.084	+5.355	<.001	.005	3	3
LIHC	PAFAH1B2P1 →	+0.071	+5.186	<.001	.007	3	2
LIHC	OR2J4P →	+0.072	+5.355	<.001	.005	3	2
LIHC	LINC01039 →	+0.103	+5.186	<.001	.007	3	2
LIHC	RN7SL335P →	+0.152	+7.914	<.001	<.001	3	2
UCEC	RN7SL248P →	+0.070	+3.400	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 813 associations by consensus.

TDGF1P1 by MRAP2 expression — LIHC

Explore this box plot interactively →