MPZ

Across TCGA patient cohorts, MPZ RNA expression is significantly associated with the protein abundance of many other proteins, with 10,130 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MPZ-associated proteins across cancer lineages are MAP1LC3A, RPS13, and RPS6KA1. Each is linked with MPZ in more than 4 cancer types. Because this analysis shows association rather than direction, both MPZ-to-partner and partner-to-MPZ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MPZ versus MAP1LC3A in LSCC, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MPZ→partner) and Y-score (partner→MPZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MAP1LC3A →	+0.618	+0.378	.001	<.001	3	5
COAD	RPS13 →	-0.209	-0.467	<.001	<.001	3	4
UCEC	RPS6KA1 →	-0.324	-0.709	<.001	<.001	3	4
HNSC	SARM1 →	+0.320	+0.640	<.001	<.001	3	4
CCRCC	SYNPO_S833 →	+0.768	+0.471	<.001	.001	3	4
HNSC	TAMALIN_S94 →	+0.445	+0.794	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,130 associations by consensus.

MPZ vs MAP1LC3A — LSCC

Explore this scatter interactively →