MPV17L2

Across TCGA patient cohorts, MPV17L2 mutation is significantly associated with the RNA expression of many other genes, with 51 significant associations in total. COAD shows the largest number of these associations.

The most reproducible MPV17L2-associated genes across cancer lineages are OR6U2P, RNU7-196P, and RNA5SP200. Each is linked with MPV17L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MPV17L2-to-partner and partner-to-MPV17L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6U2P grouped by MPV17L2-low versus MPV17L2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MPV17L2→partner) and Y-score (partner→MPV17L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	OR6U2P →	+0.117	+5.824	<.001	.001	3	2
SKCM	RNU7-196P →	+0.537	+7.816	<.001	.008	3	1
SKCM	RNA5SP200 →	+0.367	+7.816	<.001	.008	3	1
SKCM	OR7E154P →	+0.049	+7.816	<.001	.008	3	1
SKCM	LINC02729 →	+0.084	+7.816	<.001	.008	3	1
BLCA	ANKRD34C-AS1 →	+0.095	+5.588	.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

OR6U2P by MPV17L2 expression — COAD

Explore this box plot interactively →