MPV17L2

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MPV17L2 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible MPV17L2-associated genes across cancer lineages are CD4+ Tcm and NK cells. Each is linked with MPV17L2 in more than 2 cancer types. Because this analysis shows association rather than direction, both MPV17L2-to-partner and partner-to-MPV17L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tcm grouped by MPV17L2-low versus MPV17L2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MPV17L2→partner) and Y-score (partner→MPV17L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCACD4+ Tcm →+0.048+4.527<.001.01733
STADNK cells →+0.011+5.597<.001.04031
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD4+ Tcm by MPV17L2 expression — BLCA

Box plot of CD4+ Tcm in MPV17L2-low vs MPV17L2-high samples in BLCA.

Explore this box plot interactively →

Exploration