MPV17L2

Across TCGA cell cohorts, MPV17L2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,490 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MPV17L2-associated GO terms across cancer lineages are Regulation of mitochondrial translation, Positive regulation of mitochondrial translation, and Negative regulation of protein localization to chromatin. Each is linked with MPV17L2 in more than 14 cancer types. Because this analysis shows association rather than direction, both MPV17L2-to-partner and partner-to-MPV17L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitochondrial translation grouped by MPV17L2-low versus MPV17L2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MPV17L2→partner) and Y-score (partner→MPV17L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of mitochondrial translation →	+0.088	+0.625	.007	<.001	3	15
URINARY_TRACT	Positive regulation of mitochondrial translation →	+0.102	+0.673	<.001	.001	3	13
LUNG_NSCLC_LUSC	Negative regulation of protein localization to chromatin →	+0.214	+1.072	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA-templated DNA replication →	+0.080	+0.567	.005	.004	2	12
LUNG_NSCLC_LUSC	Regulation of glycolytic process through fructose-6-phosphate →	+0.143	+0.787	.007	.006	3	11
LUNG_NSCLC_LUSC	Negative regulation of glycolytic process through fructose-6-phosphate →	+0.143	+0.787	.007	.006	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,490 associations by consensus.

Regulation of mitochondrial translation by MPV17L2 expression — LUNG_SCLC

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