MPV17L2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MPV17L2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MPV17L2-associated genes across cancer lineages are PDILT and C18orf63. Each is linked with MPV17L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MPV17L2-to-partner and partner-to-MPV17L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDILT grouped by MPV17L2-low versus MPV17L2-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MPV17L2→partner) and Y-score (partner→MPV17L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUEPDILT →+0.013+5.369<.001.00431
SOFT_TISSUEC18orf63 →+0.006+5.369<.001.00431
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

PDILT by MPV17L2 expression — SOFT_TISSUE

Box plot of PDILT in MPV17L2-low vs MPV17L2-high samples in SOFT_TISSUE.

Explore this box plot interactively →

Exploration