MPV17L

Across TCGA pan-cancer cohorts, MPV17L mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated MPV17L data layer compared with 28 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher MPV17L mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated MPV17L expression acts as an unfavorable survival marker, although some lineages such as GBM and PDAC show a favorable association.

GBM and PDAC are the cancer types where MPV17L mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Median	All	0.674	0.299	.004	12	view →
PDAC	DFS	Tertile	All	0.747	0.235	.024	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

MPV17L–GBM (OS)

Open the GBM breakdown →