MPV17L

Across TCGA cell cohorts, MPV17L RNA expression is significantly associated with the go_rna of many other GO terms, with 2,541 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MPV17L-associated GO terms across cancer lineages are Negative regulation of hydrogen peroxide biosynthetic process, Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway, and Positive regulation of glucocorticoid secretion. Each is linked with MPV17L in more than 11 cancer types. Because this analysis shows association rather than direction, both MPV17L-to-partner and partner-to-MPV17L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of hydrogen peroxide biosynthetic process grouped by MPV17L-low versus MPV17L-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MPV17L→partner) and Y-score (partner→MPV17L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of hydrogen peroxide biosynthetic process →	-0.256	-0.896	<.001	<.001	3	12
LIVER	Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway →	-0.165	-1.614	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Positive regulation of glucocorticoid secretion →	+1.999	+0.637	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of cortisol secretion →	+1.736	+0.639	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cortisol secretion →	+1.736	+0.639	<.001	<.001	3	9
STOMACH	Negative regulation of hydrogen peroxide metabolic process →	-0.200	-1.307	.004	.004	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,541 associations by consensus.

Negative regulation of hydrogen peroxide biosynthetic process by MPV17L expression — OVARY

Explore this box plot interactively →