MPV17

Across TCGA patient cohorts, MPV17 protein abundance is significantly associated with the RNA expression of many other genes, with 7,368 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MPV17-associated genes across cancer lineages are EZH2, CCNB2, and CDC25A. Each is linked with MPV17 in more than 3 cancer types. Because this analysis shows association rather than direction, both MPV17-to-partner and partner-to-MPV17 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MPV17 versus EZH2 in OV, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MPV17→partner) and Y-score (partner→MPV17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	EZH2 →	-0.609	-0.281	.001	.002	3	4
UCEC	CCNB2 →	-0.659	-0.375	.001	.002	3	4
UCEC	CDC25A →	-0.845	-0.439	<.001	<.001	3	4
OV	CLSPN →	-0.740	-0.403	.005	.005	3	4
BRCA	ASCC3 →	-0.435	-0.402	.003	.002	3	4
UCEC	LMNB1 →	-0.781	-0.461	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,368 associations by consensus.

MPV17 vs EZH2 — OV

Explore this scatter interactively →