MPST

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MPST RNA expression is significantly associated with the protein abundance of many other proteins, with 12,471 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MPST-associated proteins across cancer lineages are TST, CCDC134, and EIF4ENIF1. Each is linked with MPST in more than 6 cancer types. Because this analysis shows association rather than direction, both MPST-to-partner and partner-to-MPST results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MPST versus TST in UCEC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MPST→partner) and Y-score (partner→MPST) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTST →+0.701+0.774<.001<.00137
BRCACCDC134 →+0.388+0.632.007.00436
LSCCEIF4ENIF1 →+0.237+0.707<.001<.00135
GBMTBC1D2B →-0.268-0.306<.001<.00135
LSCCTNRC6B →+0.263+0.541<.001<.00135
LSCCTACC2_S962 →+0.695+0.397<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,471 associations by consensus.

MPST vs TST — UCEC

Per-sample scatter of MPST vs TST in UCEC (Pearson r = 0.44).

Explore this scatter interactively →

Exploration