MPRIP

Across TCGA cell cohorts, MPRIP RNA expression is significantly associated with the go_rna of many other GO terms, with 5,485 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MPRIP-associated GO terms across cancer lineages are Protein depolymerization, Cell-substrate junction assembly, and Regulation of modification of postsynaptic structure. Each is linked with MPRIP in more than 13 cancer types. Because this analysis shows association rather than direction, both MPRIP-to-partner and partner-to-MPRIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein depolymerization grouped by MPRIP-low versus MPRIP-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MPRIP→partner) and Y-score (partner→MPRIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Protein depolymerization →	+0.136	+0.881	<.001	<.001	3	14
LUNG_NSCLC_LUAD	Cell-substrate junction assembly →	+0.163	+1.331	<.001	<.001	3	13
BONE	Regulation of modification of postsynaptic structure →	+0.176	+1.722	<.001	<.001	3	12
LUNG_NSCLC_LUAD	Cell-substrate junction organization →	+0.147	+1.243	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Mitotic centrosome separation →	+0.117	+0.965	<.001	.001	3	12
BONE	Positive regulation of plasma membrane repair →	+0.312	+1.301	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,485 associations by consensus.

Protein depolymerization by MPRIP expression — SKIN

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