MPPE1

Across TCGA patient cohorts, MPPE1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,035 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MPPE1-associated genes across cancer lineages are BTG3, CHCHD2P8, and NPM1P9. Each is linked with MPPE1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MPPE1-to-partner and partner-to-MPPE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MPPE1 versus BTG3 in PDAC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MPPE1→partner) and Y-score (partner→MPPE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	BTG3 →	+0.574	+0.467	.003	.003	3	3
BRCA	CHCHD2P8 →	-0.700	-0.947	.005	<.001	3	2
BRCA	NPM1P9 →	-0.825	-0.922	<.001	.001	3	2
BRCA	ABHD17AP3 →	-1.124	-0.863	<.001	<.001	3	2
BRCA	CHORDC1P4 →	-0.659	-0.693	.005	.004	3	2
BRCA	DEF8 →	-0.446	-0.652	.007	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,035 associations by consensus.

MPPE1 vs BTG3 — PDAC

Explore this scatter interactively →