MPP4

Across TCGA patient cohorts, MPP4 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,947 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible MPP4-associated proteins across cancer lineages are MMP14, CRTAP, and ANTXR1. Each is linked with MPP4 in more than 4 cancer types. Because this analysis shows association rather than direction, both MPP4-to-partner and partner-to-MPP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MPP4 versus MMP14 in PDAC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MPP4→partner) and Y-score (partner→MPP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	MMP14 →	+0.460	+0.198	<.001	<.001	3	5
OV	CRTAP →	+0.417	+0.105	<.001	<.001	3	5
PDAC	ANTXR1 →	+0.478	+0.133	<.001	<.001	3	5
CCRCC	THBS1 →	+0.713	+0.156	.001	<.001	3	4
OV	THBS2 →	+1.540	+0.122	<.001	.001	3	4
PDAC	P4HA2 →	+0.532	+0.143	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,947 associations by consensus.

MPP4 vs MMP14 — PDAC

Explore this scatter interactively →