MPP4

Across TCGA cell cohorts, MPP4 protein abundance is significantly associated with the RNA expression of many other genes, with 4,273 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MPP4-associated genes across cancer lineages are ATP6AP1, BCAP31, and ATP6V0C. Each is linked with MPP4 in more than 11 cancer types. Because this analysis shows association rather than direction, both MPP4-to-partner and partner-to-MPP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MPP4 versus ATP6AP1 in BREAST, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MPP4→partner) and Y-score (partner→MPP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	ATP6AP1 →	+1.348	+0.931	<.001	<.001	3	12
BREAST	BCAP31 →	+1.122	+0.830	<.001	<.001	3	10
PANCREAS	ATP6V0C →	+0.974	+0.758	<.001	<.001	3	10
OESOPHAGUS	SLC10A3 →	+0.974	+0.757	.002	.003	3	8
LIVER	ATP6AP2 →	+1.383	+1.373	<.001	.002	3	8
KIDNEY	FAM3A →	+0.959	+0.590	.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,273 associations by consensus.

MPP4 vs ATP6AP1 — BREAST

Explore this scatter interactively →