MPND

Across TCGA patient cohorts, MPND mutation is significantly associated with the RNA expression of many other genes, with 470 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MPND-associated genes across cancer lineages are MIR103A1, MIR1262, and SLC20A1P1. Each is linked with MPND in more than 1 cancer types. Because this analysis shows association rather than direction, both MPND-to-partner and partner-to-MPND results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR103A1 grouped by MPND-low versus MPND-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MPND→partner) and Y-score (partner→MPND) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR103A1 →	+0.870	+5.721	<.001	.001	3	2
COAD	MIR1262 →	+0.534	+4.516	.009	.009	3	2
COAD	SLC20A1P1 →	+0.080	+5.721	<.001	.001	3	2
UCEC	RNA5SP420 →	+0.703	+2.744	<.001	.001	3	2
BLCA	IFNWP9 →	+0.075	+4.033	<.001	.009	3	2
BLCA	ISCA1P2 →	+0.057	+3.236	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 470 associations by consensus.

MIR103A1 by MPND expression — COAD

Explore this box plot interactively →