MPHOSPH9

Across TCGA cell cohorts, MPHOSPH9 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,051 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MPHOSPH9-associated GO terms across cancer lineages are Regulation of G2/M transition of mitotic cell cycle, Regulation of cell cycle G2/M phase transition, and Mitotic G2/M transition checkpoint. Each is linked with MPHOSPH9 in more than 18 cancer types. Because this analysis shows association rather than direction, both MPHOSPH9-to-partner and partner-to-MPHOSPH9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of G2/M transition of mitotic cell cycle grouped by MPHOSPH9-low versus MPHOSPH9-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MPHOSPH9→partner) and Y-score (partner→MPHOSPH9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of G2/M transition of mitotic cell cycle →	+0.105	+1.665	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Regulation of cell cycle G2/M phase transition →	+0.092	+1.662	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Mitotic G2/M transition checkpoint →	+0.124	+1.631	<.001	<.001	3	19
LUNG_NSCLC_LUSC	DNA biosynthetic process →	+0.092	+1.598	<.001	.001	3	18
SKIN	Regulation of centriole-centriole cohesion →	+0.169	+1.044	<.001	<.001	3	18
URINARY_TRACT	Microtubule polymerization →	+0.113	+1.498	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,051 associations by consensus.

Regulation of G2/M transition of mitotic cell cycle by MPHOSPH9 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →