MPHOSPH6

Across TCGA patient cohorts, MPHOSPH6 RNA expression is significantly associated with the mutation status of many other genes, with 10,959 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MPHOSPH6-associated genes across cancer lineages are TP53, MUC17, and PLXNA3. Each is linked with MPHOSPH6 in more than 8 cancer types. Because this analysis shows association rather than direction, both MPHOSPH6-to-partner and partner-to-MPHOSPH6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP53 grouped by MPHOSPH6-low versus MPHOSPH6-high in SKCM.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MPHOSPH6→partner) and Y-score (partner→MPHOSPH6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TP53 →	+2.430	+0.386	<.001	<.001	3	9
STAD	MUC17 →	+2.273	+0.373	.004	.001	3	5
HNSC	PLXNA3 →	+3.830	+0.422	<.001	.008	3	4
LUSC	SACS →	+2.305	+0.412	<.001	<.001	3	4
STAD	DLC1 →	+2.803	+0.337	<.001	.006	3	4
STAD	DNAH1 →	+1.718	+0.313	.003	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,959 associations by consensus.

TP53 by MPHOSPH6 expression — SKCM

Explore this box plot interactively →