MPHOSPH6

Across TCGA cell cohorts, MPHOSPH6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,403 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MPHOSPH6-associated GO terms across cancer lineages are DNA replication initiation, RNA 5'-end processing, and Double-strand break repair via homologous recombination. Each is linked with MPHOSPH6 in more than 14 cancer types. Because this analysis shows association rather than direction, both MPHOSPH6-to-partner and partner-to-MPHOSPH6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by MPHOSPH6-low versus MPHOSPH6-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MPHOSPH6→partner) and Y-score (partner→MPHOSPH6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	DNA replication initiation →	+0.179	+0.860	<.001	<.001	3	15
BONE	RNA 5'-end processing →	+0.087	+0.677	.003	.003	3	15
BLOOD_Myeloma	Double-strand break repair via homologous recombination →	+0.067	+1.642	.002	<.001	3	13
BLOOD_Myeloma	Recombinational repair →	+0.069	+1.642	.002	<.001	3	13
BLOOD_Lymphoma	DNA strand elongation →	+0.136	+1.073	<.001	<.001	3	13
PANCREAS	DNA replication →	+0.093	+0.744	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,403 associations by consensus.

DNA replication initiation by MPHOSPH6 expression — PANCREAS

Explore this box plot interactively →