MPHOSPH10

Across TCGA pan-cancer cohorts, MPHOSPH10 Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated MPHOSPH10 data layer compared with 28 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher MPHOSPH10 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated MPHOSPH10 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

BLCA, LUAD, and UCEC are the cancer types where MPHOSPH10 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Median	III,IV	0.113	0.553	<.001	48	view →
LUAD	OS	Median	II,III,IV	0.053	0.751	<.001	36	view →
UCEC	DFS	Median	All	0.965	0.624	.011	30	view →
LIHC	OS	Median	III,IV	0.270	0.732	.021	9	view →
CESC	DFS	Median	III,IV	0.240	0.726	.015	6	view →
SKCM	DFS	Median	II,III,IV	0.046	0.708	<.001	6	view →
LUSC	OS	Median	II,III,IV	0.406	0.744	.044	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

MPHOSPH10–BLCA (DFS)

Open the BLCA breakdown →