MPHOSPH10

Across TCGA pan-cancer cohorts, MPHOSPH10 RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of MPHOSPH10’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where MPHOSPH10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MPHOSPH10 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

BLCA, KIRC, and LUSC are the cancer types where MPHOSPH10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MPHOSPH10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	IV	+0.738	<.001	12	view →
KIRC	Female	All	+0.624	<.001	11	view →
LUSC	Male	II,III,IV	+1.040	<.001	9	view →
LIHC	All	II,III,IV	+0.822	<.001	9	view →
HNSC	All	IV	+0.591	.001	9	view →
LUAD	Male	II,III,IV	+0.558	<.001	9	view →
STAD	All	II,III,IV	+0.667	<.001	8	view →
COAD	Male	All	+0.620	<.001	6	view →
BRCA	All	All	+0.360	<.001	6	view →
THCA	Male	All	−0.309	.002	6	view →
CHOL	Male	All	+1.491	<.001	5	view →
KICH	Female	All	−0.924	<.001	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

MPHOSPH10–BLCA

Open the BLCA breakdown →