MPG

Across TCGA patient cohorts, MPG protein abundance is significantly associated with the RNA expression of many other genes, with 11,412 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MPG-associated genes across cancer lineages are TFAP4, CIAO3, and UBE2I. Each is linked with MPG in more than 6 cancer types. Because this analysis shows association rather than direction, both MPG-to-partner and partner-to-MPG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MPG versus TFAP4 in OV, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MPG→partner) and Y-score (partner→MPG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TFAP4 →	+0.561	+0.309	.007	.002	3	7
BRCA	CIAO3 →	+0.543	+0.310	<.001	<.001	3	5
OV	UBE2I →	+0.690	+0.333	<.001	.001	3	5
BRCA	ZSCAN32 →	+0.344	+0.209	<.001	<.001	3	5
BRCA	POLR3K →	+0.641	+0.252	<.001	<.001	3	5
BRCA	TBL3 →	+0.649	+0.365	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,412 associations by consensus.

MPG vs TFAP4 — OV

Explore this scatter interactively →