MPDZ

Across TCGA patient cohorts, MPDZ RNA expression is significantly associated with the protein abundance of many other proteins, with 20,159 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MPDZ-associated proteins across cancer lineages are FBLN1, HDGFL3, and VCAN. Each is linked with MPDZ in more than 7 cancer types. Because this analysis shows association rather than direction, both MPDZ-to-partner and partner-to-MPDZ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MPDZ versus FBLN1 in OV, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MPDZ→partner) and Y-score (partner→MPDZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FBLN1 →	+0.852	+1.278	<.001	<.001	3	8
BRCA	HDGFL3 →	+0.823	+0.796	<.001	.001	3	8
OV	VCAN →	+1.175	+1.149	<.001	<.001	3	8
GBM	CDH13 →	+0.824	+0.617	<.001	<.001	3	7
CCRCC	AEBP1 →	+0.546	+0.438	<.001	<.001	3	7
CCRCC	CSRP1 →	+0.833	+0.585	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,159 associations by consensus.

MPDZ vs FBLN1 — OV

Explore this scatter interactively →