MPDZ

Across TCGA cell cohorts, MPDZ RNA expression is significantly associated with the go_rna of many other GO terms, with 3,340 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MPDZ-associated GO terms across cancer lineages are Spliceosomal complex assembly, Centrosome cycle, and Protein-DNA complex organization. Each is linked with MPDZ in more than 11 cancer types. Because this analysis shows association rather than direction, both MPDZ-to-partner and partner-to-MPDZ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spliceosomal complex assembly grouped by MPDZ-low versus MPDZ-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MPDZ→partner) and Y-score (partner→MPDZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Spliceosomal complex assembly →	+0.155	+2.576	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Centrosome cycle →	+0.098	+2.036	<.001	<.001	3	11
OESOPHAGUS	Protein-DNA complex organization →	+0.044	+1.869	.007	<.001	3	11
OVARY	Transcription initiation at RNA polymerase II promoter →	+0.050	+1.679	.008	<.001	3	11
STOMACH	Protein localization to nucleus →	+0.058	+1.648	<.001	.008	2	11
STOMACH	Nuclear transport →	+0.062	+1.377	.001	.009	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,340 associations by consensus.

Spliceosomal complex assembly by MPDZ expression — OESOPHAGUS

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