MPC2

Across TCGA patient cohorts, MPC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,194 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MPC2-associated proteins across cancer lineages are PLEKHA6, SCAMP3, and TIPRL. Each is linked with MPC2 in more than 5 cancer types. Because this analysis shows association rather than direction, both MPC2-to-partner and partner-to-MPC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MPC2 versus PLEKHA6 in LUAD, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MPC2→partner) and Y-score (partner→MPC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PLEKHA6 →	+0.601	+0.526	<.001	<.001	3	6
BRCA	SCAMP3 →	+0.331	+0.478	<.001	.003	3	6
OV	TIPRL →	+0.468	+0.530	<.001	.005	3	6
UCEC	TSTD1 →	+0.492	+0.644	<.001	<.001	3	6
LSCC	RAB31 →	-0.356	-0.584	<.001	.002	3	5
UCEC	BPNT1 →	+0.501	+0.964	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,194 associations by consensus.

MPC2 vs PLEKHA6 — LUAD

Explore this scatter interactively →