MPC2

Across TCGA patient cohorts, MPC2 protein abundance is significantly associated with the RNA expression of many other genes, with 7,537 significant associations in total. COAD shows the largest number of these associations.

The most reproducible MPC2-associated genes across cancer lineages are MPC1, CHST14, and TMEM45A. Each is linked with MPC2 in more than 6 cancer types. Because this analysis shows association rather than direction, both MPC2-to-partner and partner-to-MPC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MPC2 versus MPC1 in OV, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MPC2→partner) and Y-score (partner→MPC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MPC1 →	+0.604	+0.515	<.001	<.001	3	7
OV	CHST14 →	-0.634	-0.329	<.001	.003	3	5
HNSC	TMEM45A →	-1.216	-0.408	<.001	<.001	3	4
COAD	KDM3A →	-0.432	-0.295	<.001	.003	3	4
COAD	PDGFB →	-0.758	-0.377	.001	<.001	3	4
COAD	SPOCK1 →	-0.889	-0.310	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,537 associations by consensus.

MPC2 vs MPC1 — OV

Explore this scatter interactively →