MOXD2P

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MOXD2P mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MOXD2P-associated genes across cancer lineages are RN7SKP214, RNU6-354P, and RPS3AP33. Each is linked with MOXD2P in more than 1 cancer types. Because this analysis shows association rather than direction, both MOXD2P-to-partner and partner-to-MOXD2P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP214 grouped by MOXD2P-low versus MOXD2P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MOXD2P→partner) and Y-score (partner→MOXD2P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRN7SKP214 →+0.323+3.334<.001<.00131
UCECRNU6-354P →+0.366+3.316.003.00231
UCECRPS3AP33 →+0.079+3.203<.001.00331
UCECISCA1P1 →+0.338+3.791.002.00331
UCECMIR1180 →+0.596+3.061.002.00231
UCECRNA5SP247 →+0.672+2.679<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

RN7SKP214 by MOXD2P expression — UCEC

Box plot of RN7SKP214 in MOXD2P-low vs MOXD2P-high samples in UCEC.

Explore this box plot interactively →

Exploration