MOXD1

Across TCGA patient cohorts, MOXD1 mutation is significantly associated with the RNA expression of many other genes, with 3,435 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MOXD1-associated genes across cancer lineages are FN3KRP, OR1R1P, and RNA5SP441. Each is linked with MOXD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MOXD1-to-partner and partner-to-MOXD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FN3KRP grouped by MOXD1-low versus MOXD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MOXD1→partner) and Y-score (partner→MOXD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FN3KRP →	+0.358	+2.255	.004	<.001	3	3
READ	OR1R1P →	+0.068	+6.681	<.001	<.001	3	2
READ	RNA5SP441 →	+1.006	+5.219	<.001	.006	3	2
SKCM	MIR5585 →	+0.275	+2.321	.003	.002	3	2
BRCA	MIR139 →	+0.516	+7.731	<.001	.009	3	2
SKCM	HPS1 →	+0.566	+3.506	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,435 associations by consensus.

FN3KRP by MOXD1 expression — UCEC

Explore this box plot interactively →