MOXD1

Across TCGA pan-cancer cohorts, MOXD1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of MOXD1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MOXD1 RNA is repressed in tumor relative to normal tissue. In most cancer types MOXD1 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, KICH, and BRCA are the cancer types where MOXD1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MOXD1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−2.812	<.001	12	view →
KICH	Female	II,III,IV	−4.604	<.001	8	view →
BRCA	All	II,III,IV	+0.961	<.001	6	view →
KIRP	Male	All	−1.658	<.001	5	view →
LUAD	All	All	+0.611	<.001	5	view →
BLCA	Male	All	−1.600	.007	4	view →
THCA	All	All	−0.423	.005	4	view →
LUSC	Male	II,III,IV	−1.179	.009	3	view →
CHOL	All	All	+1.702	.004	1	view →
HNSC	Male	II,III,IV	−0.776	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

MOXD1–KIRC

Open the KIRC breakdown →