MOXD1

Across TCGA cell cohorts, MOXD1 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MOXD1-associated genes across cancer lineages are CSN2, DYNAP, and SI. Each is linked with MOXD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MOXD1-to-partner and partner-to-MOXD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CSN2 grouped by MOXD1-low versus MOXD1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MOXD1→partner) and Y-score (partner→MOXD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CSN2 →	+0.017	+4.969	<.001	.003	3	1
BLOOD_Leukemia	DYNAP →	+0.718	+4.152	<.001	.009	3	1
BLOOD_Leukemia	SI →	+0.069	+4.539	<.001	.007	3	1
OVARY	H2AP →	+0.215	+5.196	<.001	.005	3	1
OVARY	OR4D2 →	+0.016	+5.196	<.001	.005	3	1
LARGE_INTESTINE	SMAP1 →	+0.826	+3.067	.007	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

CSN2 by MOXD1 expression — BLOOD_Leukemia

Explore this box plot interactively →