MOV10L1

Across TCGA pan-cancer cohorts, MOV10L1 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated MOV10L1 data layer compared with 16 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher MOV10L1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated MOV10L1 expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.

PAAD, PRAD, and KIRP are the cancer types where MOV10L1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	OS	Median	All	0.060	0.641	<.001	12	view →
PRAD	OS	Median	All	0.826	0.990	<.001	8	view →
KIRP	DFS	Median	All	0.508	0.919	.041	2	view →
GBM	OS	Median	All	1.000	0.312	.048	2	view →
COAD	OS	Median	All	0.717	0.877	.035	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

MOV10L1–PAAD (OS)

Open the PAAD breakdown →