MOV10L1

Across TCGA patient cohorts, MOV10L1 mutation is significantly associated with the total protein of many other genes, with 52 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MOV10L1-associated genes across cancer lineages are Bim, ERK2, and INPP4B. Each is linked with MOV10L1 in more than 3 cancer types. Because this analysis shows association rather than direction, both MOV10L1-to-partner and partner-to-MOV10L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Bim grouped by MOV10L1-low versus MOV10L1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MOV10L1→partner) and Y-score (partner→MOV10L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Bim →	-0.189	-1.874	.048	.047	3	4
UCEC	ERK2 →	+0.166	+1.643	.005	.003	3	3
UCEC	INPP4B →	-0.216	-1.401	.031	.010	3	3
BRCA	ASNS →	+0.596	+3.169	.001	.020	3	2
BRCA	4E-BP1 →	+0.454	+2.827	.012	.036	3	2
SKCM	HER3_pY1289 →	-0.069	-1.874	.042	.049	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

Bim by MOV10L1 expression — SKCM

Explore this box plot interactively →