MOV10L1

Across TCGA cell cohorts, MOV10L1 mutation is significantly associated with the RNA expression of many other genes, with 328 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MOV10L1-associated genes across cancer lineages are GUCA1A, CD300H, and OR10Q1. Each is linked with MOV10L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MOV10L1-to-partner and partner-to-MOV10L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GUCA1A grouped by MOV10L1-low versus MOV10L1-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MOV10L1→partner) and Y-score (partner→MOV10L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	GUCA1A →	+0.112	+3.754	<.001	.005	3	2
LARGE_INTESTINE	CD300H →	+0.018	+2.830	<.001	.004	3	2
SOFT_TISSUE	OR10Q1 →	+0.167	+4.930	<.001	.008	3	1
STOMACH	IL17F →	+0.373	+4.070	.003	.006	3	1
STOMACH	IDI2 →	+0.023	+3.794	<.001	.003	3	1
STOMACH	RIT2 →	+0.325	+3.432	.007	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 328 associations by consensus.

GUCA1A by MOV10L1 expression — STOMACH

Explore this box plot interactively →