MOS

Across TCGA patient cohorts, MOS RNA expression is significantly associated with the go_rna of many other GO terms, with 6,360 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MOS-associated GO terms across cancer lineages are Ribose phosphate biosynthetic process, Mitochondrial respiratory chain complex assembly, and NADH dehydrogenase complex assembly. Each is linked with MOS in more than 8 cancer types. Because this analysis shows association rather than direction, both MOS-to-partner and partner-to-MOS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribose phosphate biosynthetic process grouped by MOS-low versus MOS-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MOS→partner) and Y-score (partner→MOS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Ribose phosphate biosynthetic process →	+0.054	+0.057	<.001	<.001	3	9
STAD	Mitochondrial respiratory chain complex assembly →	+0.062	+0.064	<.001	<.001	3	8
STAD	NADH dehydrogenase complex assembly →	+0.064	+0.047	<.001	<.001	3	7
STAD	Cytoplasmic translation →	+0.073	+0.055	<.001	<.001	3	7
STAD	RNA capping →	+0.050	+0.060	<.001	<.001	3	7
STAD	Mitochondrial depolarization →	+0.045	+0.099	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,360 associations by consensus.

Ribose phosphate biosynthetic process by MOS expression — STAD

Explore this box plot interactively →