MORN4

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MORN4 mutation is significantly associated with the RNA expression of many other genes, with 2,118 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MORN4-associated genes across cancer lineages are RNA5SP302, RNA5SP176, and RNY4P27. Each is linked with MORN4 in more than 2 cancer types. Because this analysis shows association rather than direction, both MORN4-to-partner and partner-to-MORN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP302 grouped by MORN4-low versus MORN4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MORN4→partner) and Y-score (partner→MORN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP302 →+1.063+2.339<.001.00533
UCECRNA5SP176 →+0.432+3.923<.001.00132
UCECRNY4P27 →+0.155+3.132<.001.00532
UCECRNA5SP424 →+0.172+2.434.005.00932
UCECRAB28P3 →+0.111+2.492<.001.00832
UCECRNA5SP518 →+0.145+4.060<.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,118 associations by consensus.

RNA5SP302 by MORN4 expression — UCEC

Box plot of RNA5SP302 in MORN4-low vs MORN4-high samples in UCEC.

Explore this box plot interactively →

Exploration