MORN1

Across TCGA patient cohorts, MORN1 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MORN1-associated genes across cancer lineages are ATM, eEF2, and EGFR_pY1068. Each is linked with MORN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MORN1-to-partner and partner-to-MORN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by MORN1-low versus MORN1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MORN1→partner) and Y-score (partner→MORN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.539	-1.906	.003	.016	3	2
UCEC	eEF2 →	+0.413	+2.415	.004	.003	3	1
UCEC	EGFR_pY1068 →	-0.205	-3.087	.042	<.001	3	1
UCEC	A-Raf_pS299 →	-0.151	-3.169	.001	.019	3	1
UCEC	ERK2 →	+0.157	+1.874	.042	.049	3	1
UCEC	ETS-1 →	+0.302	+2.415	.018	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

ATM by MORN1 expression — UCEC

Explore this box plot interactively →