MORN1

Across TCGA cell cohorts, MORN1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MORN1-associated genes across cancer lineages are PAX4, OR2T5, and C1orf141. Each is linked with MORN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MORN1-to-partner and partner-to-MORN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PAX4 grouped by MORN1-low versus MORN1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MORN1→partner) and Y-score (partner→MORN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	PAX4 →	+0.022	+4.930	<.001	.008	3	1
BREAST	OR2T5 →	+0.033	+5.781	<.001	.001	3	1
BREAST	C1orf141 →	+0.049	+5.781	<.001	.001	3	1
BREAST	FOXB2 →	+0.042	+5.169	<.001	.005	3	1
LARGE_INTESTINE	TBC1D21 →	+0.015	+5.022	<.001	.002	3	1
LARGE_INTESTINE	LCE1F →	+0.122	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

PAX4 by MORN1 expression — SOFT_TISSUE

Explore this box plot interactively →