MORC4

Across TCGA cell cohorts, MORC4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,868 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MORC4-associated GO terms across cancer lineages are Post-Golgi vesicle-mediated transport, Negative regulation of cell cycle phase transition, and Golgi to lysosome transport. Each is linked with MORC4 in more than 9 cancer types. Because this analysis shows association rather than direction, both MORC4-to-partner and partner-to-MORC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Post-Golgi vesicle-mediated transport grouped by MORC4-low versus MORC4-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MORC4→partner) and Y-score (partner→MORC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Post-Golgi vesicle-mediated transport →	+0.051	+0.704	<.001	<.001	3	10
BLOOD_Leukemia	Negative regulation of cell cycle phase transition →	+0.057	+0.855	<.001	.004	3	8
LARGE_INTESTINE	Golgi to lysosome transport →	+0.071	+1.008	<.001	<.001	3	7
OVARY	Response to UV →	+0.031	+1.069	.003	.005	3	7
LUNG_SCLC	Golgi vesicle transport →	+0.059	+0.908	<.001	<.001	3	7
PANCREAS	Vesicle tethering →	+0.041	+0.936	.003	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,868 associations by consensus.

Post-Golgi vesicle-mediated transport by MORC4 expression — LUNG_SCLC

Explore this box plot interactively →