MORC3

Across TCGA patient cohorts, MORC3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,853 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MORC3-associated proteins across cancer lineages are NDUFAF4, YARS2, and SUPV3L1. Each is linked with MORC3 in more than 4 cancer types. Because this analysis shows association rather than direction, both MORC3-to-partner and partner-to-MORC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MORC3 versus NDUFAF4 in BRCA, with a Pearson correlation of -0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MORC3→partner) and Y-score (partner→MORC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NDUFAF4 →	-0.289	-0.477	<.001	<.001	3	5
OV	YARS2 →	-0.363	-0.434	.003	.001	3	4
BRCA	SUPV3L1 →	-0.277	-0.559	<.001	<.001	3	4
OV	TFB2M →	-0.545	-0.553	.001	<.001	3	4
COAD	PMPCB →	-0.290	-0.412	<.001	<.001	3	4
GBM	RPL7 →	-0.407	-0.288	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,853 associations by consensus.

MORC3 vs NDUFAF4 — BRCA

Explore this scatter interactively →