MORC1

Across TCGA patient cohorts, MORC1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,505 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MORC1-associated genes across cancer lineages are DES, ITGA7, and PLCL1. Each is linked with MORC1 in more than 3 cancer types. Because this analysis shows association rather than direction, both MORC1-to-partner and partner-to-MORC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MORC1 versus DES in HNSC, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MORC1→partner) and Y-score (partner→MORC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DES →	+2.431	+0.706	<.001	<.001	3	4
HNSC	ITGA7 →	+1.322	+1.038	<.001	<.001	3	3
OV	PLCL1 →	+0.780	+0.752	<.001	.004	3	2
HNSC	LDB3 →	+1.016	+0.643	<.001	<.001	3	2
HNSC	KLHL40 →	+0.926	+0.624	<.001	<.001	3	2
HNSC	SYNPO2L →	+0.807	+0.768	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,505 associations by consensus.

MORC1 vs DES — HNSC

Explore this scatter interactively →