MORC1

Across TCGA cell cohorts, MORC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 421 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MORC1-associated GO terms across cancer lineages are Growth involved in heart morphogenesis, Positive regulation of cellular response to hypoxia, and Quinone biosynthetic process. Each is linked with MORC1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MORC1-to-partner and partner-to-MORC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Growth involved in heart morphogenesis grouped by MORC1-low versus MORC1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MORC1→partner) and Y-score (partner→MORC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Growth involved in heart morphogenesis →	-0.996	-0.994	<.001	.008	3	3
BONE	Positive regulation of cellular response to hypoxia →	+0.845	+0.393	.003	.007	3	3
BONE	Quinone biosynthetic process →	+0.074	+0.278	<.001	.008	3	3
BONE	Ketone biosynthetic process →	+0.072	+0.278	<.001	.008	3	3
BONE	Ubiquinone biosynthetic process →	+0.074	+0.278	<.001	.008	3	3
SKIN	Natural killer cell mediated cytotoxicity →	+0.096	+0.431	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 421 associations by consensus.

Growth involved in heart morphogenesis by MORC1 expression — BLOOD_Myeloma

Explore this box plot interactively →